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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3117 Species: Rattus norvegicus RGD Object: Gene Symbol: Mt1a Name: metallothionein 1a

Acc ID: CHEBI:53001 Term: nickel sulfate Definition: A metal sulfate compound having nickel(2+) as the counterion. CasRN: 7786-81-4 Chemical ID: MESH:C029938

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:10922	6480464	CTD	nickel sulfate affects the expression of MT1 mRNA	PMID:12718980
increases expression	EXP		6480464	CTD	nickel sulfate results in increased expression of MT1A mRNA	PMID:19679144