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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:52497
Term: maneb
Definition: A polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. An agrochemical fungicide, it is used to control a variety of diseases including blight, leaf spot, rust, downy mildew and scab.
Chemical ID: MESH:D008344
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1increases expressionISOBCL2L1 (Homo sapiens)6480464CTDManeb results in increased expression of BCL2L1 mRNAPMID:18266926
Bcl2l1multiple interactionsISOBCL2L1 (Homo sapiens)6480464CTD[Paraquat co-treated with Maneb] results in decreased expression of BCL2L1 proteinPMID:15824117
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