GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | decreases reaction | EXP | | 152177689 | RGD | wortmannin inhibits the reaction [estrogen increases expression of Vegfa mRNA] in rat uterus | | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | [4'-hydroxywogonin co-treated with Wortmannin] inhibits the reaction [IL6 protein results in increased expression of and results in increased secretion of VEGFA protein]; [4'-hydroxywogonin co-treated with Wortmannin] inhibits the reaction [IL6 protein results in increased expression of VEGFA mRNA]; Wortmannin inhibits the reaction [4-hydroxyestradiol results in increased expression of VEGFA protein]; Wortmannin inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; Wortmannin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA protein]; Wortmannin inhibits the reaction [CYP4Z1 protein results in increased expression of VEGFA mRNA]; Wortmannin inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [Estradiol results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [Genistein results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [IGF1 protein results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [IL6 protein results in increased expression of and results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [IL6 protein results in increased expression of VEGFA mRNA]; Wortmannin inhibits the reaction [Oxaliplatin results in increased expression of VEGFA protein]; Wortmannin inhibits the reaction [sodium arsenite results in increased expression of VEGFA protein]; Wortmannin inhibits the reaction [tetrachlorodian results in increased expression of VEGFA mRNA] | PMID:13679210 PMID:15050414 PMID:16499871 PMID:18252963 PMID:18790786 PMID:22841774 PMID:23968725 PMID:30217479 PMID:36190352 | |
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