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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3696
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc1a1
Name: solute carrier family 1 member 1
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc1a1decreases activityEXP 6480464CTDwortmannin results in decreased activity of SLC1A1 proteinPMID:23262392 PMID:23602688 PMID:24355585
Slc1a1multiple interactionsEXP 6480464CTDwortmannin inhibits the reaction [Carbamazepine results in increased activity of SLC1A1 protein]; wortmannin inhibits the reaction [Pregabalin results in increased activity of SLC1A1 protein]; wortmannin inhibits the reaction [Progesterone results in increased activity of SLC1A1 protein]PMID:16150575 PMID:22511482 PMID:23602688
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