Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	61867
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Casp9
Name:	caspase 9

Acc ID:	CHEBI:52172
Term:	nilotinib
Definition:	A carboxamide that has formula C28H22F3N7O.
Chemical ID:	MESH:C498826

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Casp9	increases cleavage	ISO	CASP9 (Homo sapiens)	6480464	CTD	nilotinib results in increased cleavage of CASP9 protein	PMID:26549707

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.