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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:51913
Term: Goe 6976
Definition: An indolocarbazole that has formula C24H18N4O.
Chemical ID: MESH:C081021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1multiple interactionsEXP 6480464CTDGo 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]PMID:12720544
Mapk1decreases phosphorylationISOMapk1 (Mus musculus)6480464CTDGo 6976 results in decreased phosphorylation of MAPK1 proteinPMID:19393235
Mapk1multiple interactionsISOMAPK1 (Homo sapiens)6480464CTDGo 6976 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]PMID:16251475 PMID:20152819 PMID:21354279 PMID:28087840
Mapk1multiple interactionsISOMapk1 (Mus musculus)6480464CTDGo 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]PMID:14511371
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