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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1
Acc ID: CHEBI:51687
Term: chrysene
Definition: An ortho-fused polycyclic arene found commonly in the coal tar.
Chemical ID: MESH:C031180
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1increases expressionISOESR1 (Homo sapiens)6480464CTDchrysene results in increased expression of ESR1 mRNAPMID:11922773
Esr1multiple interactionsISOESR1 (Homo sapiens)6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with chrysene] results in increased expression of ESR1 mRNAPMID:11922773
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