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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621700
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sftpb
Name: surfactant protein B
Acc ID: CHEBI:51450
Term: bosentan
Definition: A pyrimidine that has formula C27H29N5O6S.
Chemical ID: MESH:C086232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sftpbmultiple interactionsEXP 6480464CTDbosentan inhibits the reaction [Nitric Oxide Donors results in decreased expression of SFTPB mRNA]; bosentan inhibits the reaction [Nitric Oxide results in decreased expression of SFTPB mRNA]; bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPB mRNA]PMID:15640287
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