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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
Acc ID: CHEBI:5132
Term: flutamide
Definition: A (trifluoromethyl)benzene that has formula C11H11F3N2O3.
Chemical ID: MESH:D005485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr3c1decreases expressionEXP 6480464CTDFlutamide results in decreased expression of NR3C1 mRNAPMID:24136188
Nr3c1multiple interactionsISONR3C1 (Homo sapiens)6480464CTDFlutamide inhibits the reaction [Dehydroepiandrosterone results in increased expression of NR3C1 protein]PMID:27239218
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