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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737311 Species: Homo sapiens RGD Object: Gene Symbol: VHL Name: von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase

Acc ID: CHEBI:50866 Term: 3H-1,2-dithiole-3-thione Definition: A 1,2-dithiole that has formula C3H2S3. CasRN: 534-25-8 Chemical ID: MESH:C049325

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:3960	6480464	CTD	1,2-dithiol-3-thione results in decreased expression of VHL mRNA	PMID:19162173