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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:507499
Term: tricetin
Definition: Flavone hydroxylated at positions 3', 4', 5, 5' and 7.
Chemical ID: MESH:C469689
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9decreases expressionISOMMP9 (Homo sapiens)6480464CTDtricetin results in decreased expression of MMP9 mRNA; tricetin results in decreased expression of MMP9 proteinPMID:27860196
Mmp9multiple interactionsISOMMP9 (Homo sapiens)6480464CTDtricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]PMID:28731287
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