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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aifm1
Name: apoptosis inducing factor, mitochondria associated 1
Acc ID: CHEBI:50694
Term: minocycline
Definition: A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5.
Chemical ID: MESH:D008911
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aifm1multiple interactionsEXP 6480464CTDMinocycline inhibits the reaction [HTT protein mutant form results in increased secretion of and results in increased localization of AIFM1 protein]PMID:12930891
Aifm1decreases secretionISOAifm1 (Mus musculus)6480464CTDMinocycline results in decreased secretion of AIFM1 proteinPMID:12930891
Aifm1multiple interactionsISOAifm1 (Mus musculus)6480464CTDMinocycline inhibits the reaction [Kainic Acid results in increased localization of AIFM1 protein]PMID:16469440
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