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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2623
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fmr1
Name: fragile X messenger ribonucleoprotein 1
Acc ID: CHEBI:50694
Term: minocycline
Definition: A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5.
Chemical ID: MESH:D008911
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fmr1multiple interactionsISOFmr1 (Mus musculus)6480464CTDMinocycline inhibits the reaction [FMR1 gene mutant form results in increased expression of and results in increased activity of MMP9 protein]PMID:18835858
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