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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732272 Species: Mus musculus RGD Object: Gene Symbol: Mapk8 Name: mitogen-activated protein kinase 8

Acc ID: CHEBI:50692 Term: mifepristone Definition: A 3-oxo steroid that has formula C29H35NO2. CasRN: 84371-65-3 Chemical ID: MESH:D015735

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:732271	6480464	CTD	Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]]	PMID:10807665