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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:50692
Term: mifepristone
Definition: A 3-oxo steroid that has formula 429.59374.
Chemical ID: MESH:D015735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9multiple interactionsEXP 6480464CTDMifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MMP9 protein]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Hydrogen Sulfide results in increased expression of MMP9 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Hydrogen Sulfide results in increased expression of MMP9 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]]PMID:15963473 PMID:24722316 PMID:30229846
Mmp9multiple interactionsISOMMP9 (Homo sapiens)6480464CTDMifepristone inhibits the reaction [Dexamethasone inhibits the reaction [sodium bisulfide results in increased expression of MMP9 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [sodium bisulfide results in increased expression of MMP9 protein]]; Mifepristone inhibits the reaction [Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]]PMID:18722610 PMID:24722316
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