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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:50692
Term: mifepristone
Definition: A 3-oxo steroid that has formula 429.59374.
Chemical ID: MESH:D015735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1decreases expressionEXP 6480464CTDMifepristone results in decreased expression of HMOX1 mRNAPMID:25972201
Hmox1multiple interactionsEXP 6480464CTD[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA]PMID:24812154
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