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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2202
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdnf
Name: brain-derived neurotrophic factor
Acc ID: CHEBI:50692
Term: mifepristone
Definition: A 3-oxo steroid that has formula 429.59374.
Chemical ID: MESH:D015735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdnfmultiple interactionsEXP 6480464CTDMifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Arsanilic Acid results in decreased expression of BDNF mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Arsanilic Acid results in decreased expression of BDNF protein]]; Mifepristone inhibits the reaction [Dexamethasone results in decreased acetylation of BDNF exon]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of BDNF mRNA]PMID:30628712 PMID:31518422
Bdnfdecreases expressionISOBDNF (Homo sapiens)6480464CTDMifepristone results in decreased expression of BDNF proteinPMID:17464718
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