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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3224
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a1
Name: solute carrier family 22 member 1
Acc ID: CHEBI:50686
Term: atorvastatin calcium
Definition: An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio.
Chemical ID: MESH:D000069059
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a1increases expressionISOSlc22a1 (Mus musculus)6480464CTDAtorvastatin results in increased expression of SLC22A1 mRNAPMID:25278499
Slc22a1multiple interactionsISOSLC22A1 (Homo sapiens)6480464CTDAtorvastatin inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]PMID:21641380
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