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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737082 Species: Homo sapiens RGD Object: Gene Symbol: CD80 Name: CD80 molecule

Acc ID: CHEBI:50648 Term: 9-cis-retinoic acid Definition: A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry. CasRN: 5300-03-8 Chemical ID: MESH:C103303

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	2-chloro-5-nitrobenzanilide inhibits the reaction [alitretinoin results in decreased expression of CD80 protein] [alitretinoin co-treated with rosiglitazone] results in decreased expression of CD80 protein HX 630 inhibits the reaction [alitretinoin results in decreased expression of CD80 protein]	PMID:17475839
decreases expression	EXP		6480464	CTD	alitretinoin results in decreased expression of CD80 protein	PMID:17475839