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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2686
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gh1
Name: growth hormone 1
Acc ID: CHEBI:50648
Term: 9-cis-retinoic acid
Definition: A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.
Chemical ID: MESH:C103303
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gh1increases expressionEXP 6480464CTDAlitretinoin results in increased expression of GH1 mRNAPMID:10720163 PMID:15240998 PMID:17090972
Gh1multiple interactionsEXP 6480464CTDAlitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Pentetic Acid promotes the reaction [Alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]; Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]]; Triiodothyronine promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]]]PMID:10720163
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