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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:5062
Term: finasteride
Definition: An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.
Chemical ID: MESH:D018120
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2multiple interactionsEXP 6480464CTDFinasteride inhibits the reaction [testosterone enanthate results in increased expression of BCL2 mRNA]; Finasteride inhibits the reaction [testosterone enanthate results in increased expression of BCL2 protein]; Finasteride inhibits the reaction [Testosterone results in increased expression of BCL2 protein]PMID:25714330 PMID:27687055 PMID:27866977 PMID:36015278
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