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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsISONFE2L2 (Homo sapiens)6480464CTDDecitabine inhibits the reaction [sodium arsenite results in increased expression of NFE2L2 protein]PMID:26409248
Nfe2l2multiple interactionsISONfe2l2 (Mus musculus)6480464CTD[Decitabine co-treated with trichostatin A] results in decreased methylation of NFE2L2 promoter; [trichostatin A co-treated with Decitabine] results in decreased methylation of NFE2L2 promoterPMID:26991801 PMID:31181187
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