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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314438 Species: Homo sapiens RGD Object: Gene Symbol: RRM2B Name: ribonucleotide reductase M2 B (TP53 inducible)

Acc ID: CHEBI:50131 Term: 5-aza-2'-deoxycytidine Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4. CasRN: 2353-33-5 Chemical ID: MESH:C014347

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	decitabine results in increased expression of RRM2B protein decitabine results in increased expression of RRM2B mRNA	PMID:19010910
multiple interactions	EXP		6480464	CTD	TP53 protein affects the reaction [decitabine results in increased expression of RRM2B mRNA]	PMID:19010910