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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71039 Species: Rattus norvegicus RGD Object: Gene Symbol: Mgll Name: monoglyceride lipase

Acc ID: CHEBI:50122 Term: rosiglitazone Definition: A thiazolidenedione that has formula C18H19N3O3S. CasRN: 122320-73-4 Chemical ID: MESH:C089730

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:737065	6480464	CTD	[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGLL mRNA Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGLL mRNA]	PMID:16054899
increases expression	EXP		6480464	CTD	rosiglitazone results in increased expression of MGLL mRNA	PMID:21172411
increases expression	EXP		6480464	CTD	rosiglitazone results in increased expression of MGLL mRNA	PMID:21172411 PMID:21515302