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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3074 Species: Rattus norvegicus RGD Object: Gene Symbol: Me1 Name: malic enzyme 1, NADP(+)-dependent, cytosolic

Acc ID: CHEBI:50122 Term: rosiglitazone Definition: A thiazolidenedione that has formula C18H19N3O3S. CasRN: 122320-73-4 Chemical ID: MESH:C089730

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	rosiglitazone results in increased expression of ME1 mRNA	PMID:19201733
decreases expression	ISO	RGD:10890	6480464	CTD	rosiglitazone results in decreased expression of ME1 mRNA	PMID:17361034