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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1607086 Species: Homo sapiens RGD Object: Gene Symbol: SKP2 Name: S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

Acc ID: CHEBI:50122 Term: rosiglitazone Definition: A thiazolidenedione that has formula C18H19N3O3S. CasRN: 122320-73-4 Chemical ID: MESH:C089730

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1552631	6480464	CTD	rosiglitazone results in decreased expression of SKP2 mRNA	PMID:17077279