• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11062 Species: Mus musculus RGD Object: Gene Symbol: Pck1 Name: phosphoenolpyruvate carboxykinase 1, cytosolic

Acc ID: CHEBI:50122 Term: rosiglitazone Definition: A thiazolidenedione that has formula C18H19N3O3S. CasRN: 122320-73-4 Chemical ID: MESH:C089730

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases activity	ISO	RGD:1347922	6480464	CTD	rosiglitazone results in increased activity of PCK1 protein	PMID:14739078
increases expression	ISO	RGD:1347922	6480464	CTD	rosiglitazone results in increased expression of PCK1 mRNA	PMID:14739078
multiple interactions	ISO	RGD:3267	6480464	CTD	rosiglitazone inhibits the reaction [Fructose results in increased expression of PCK1 mRNA] rosiglitazone inhibits the reaction [Fructose results in increased expression of PCK1 protein]	PMID:19196556
increases expression	ISO	RGD:3267	6480464	CTD	rosiglitazone results in increased expression of PCK1 mRNA	PMID:19211718
multiple interactions	EXP		6480464	CTD	[Isoproterenol co-treated with rosiglitazone] results in increased expression of PCK1 mRNA Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [rosiglitazone results in increased expression of PCK1 mRNA]]	PMID:9518257
increases expression	EXP		6480464	CTD	rosiglitazone results in increased expression of PCK1 mRNA	PMID:9518257
increases expression	ISO	RGD:3267	6480464	CTD	rosiglitazone results in increased expression of PCK1 mRNA	PMID:19211718 PMID:9518257
increases expression	ISO	RGD:3267	6480464	CTD	rosiglitazone results in increased expression of PCK1 mRNA	PMID:9518257 PMID:19211718
increases expression	ISO	RGD:3267	6480464	CTD	rosiglitazone results in increased expression of PCK1 mRNA	PMID:19211718 PMID:21515302 PMID:9518257