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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:50103
Term: excitatory amino acid agonist
Definition: An agent that binds to and activates excitatory amino acid receptors.
Chemical ID: MESH:D018690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1decreases phosphorylationEXP 6480464CTDExcitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 proteinPMID:19201465
Akt1multiple interactionsEXP 6480464CTDmangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein]PMID:19201465
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