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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11219 Species: Mus musculus RGD Object: Gene Symbol: Rb1 Name: retinoblastoma 1

Acc ID: CHEBI:50102 Term: N-methyl-N-nitrosurea Definition: An urea that has formula C2H5N3O2. CasRN: 684-93-5 Chemical ID: MESH:D008770

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases phosphorylation	ISO	RGD:3540	6480464	CTD	Methylnitrosourea results in increased phosphorylation of RB1 protein	PMID:15581186