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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acaa1a
Name: acetyl-CoA acyltransferase 1A
Acc ID: CHEBI:5001
Term: fenofibrate
Definition: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Chemical ID: MESH:D011345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acaa1aaffects expressionEXP 6480464CTDFenofibrate affects the expression of ACAA1A mRNAPMID:20801182
Acaa1aincreases expressionEXP 6480464CTDFenofibrate results in increased expression of ACAA1 mRNA; Fenofibrate results in increased expression of ACAA1A mRNAPMID:27071702 PMID:32741897
Acaa1amultiple interactionsEXP 6480464CTDFenofibrate promotes the reaction [Pyrazinamide results in increased expression of ACAA1 mRNA]; Pyrazinamide promotes the reaction [Fenofibrate results in increased expression of ACAA1 mRNA]PMID:27071702
Acaa1aincreases expressionISOACAA1 (Homo sapiens)6480464CTDFenofibrate results in increased expression of ACAA1 mRNAPMID:24752549
Acaa1aincreases expressionISOAcaa1a (Mus musculus)6480464CTDFenofibrate results in increased expression of ACAA1A mRNAPMID:11798191
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