GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Eif2ak3 | increases phosphorylation | EXP | | 6480464 | CTD | Arsenic Trioxide results in increased phosphorylation of EIF2AK3 protein | PMID:29111283 | Eif2ak3 | increases expression | ISO | EIF2AK3 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of EIF2AK3 mRNA; Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form | PMID:17963750 PMID:22922937 | Eif2ak3 | increases expression | ISO | Eif2ak3 (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form | PMID:27638049 | Eif2ak3 | increases phosphorylation | ISO | Eif2ak3 (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in increased phosphorylation of EIF2AK3 protein | PMID:29111283 | Eif2ak3 | multiple interactions | ISO | EIF2AK3 (Homo sapiens) | 6480464 | CTD | sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form] | PMID:22922937 | Eif2ak3 | multiple interactions | ISO | Eif2ak3 (Mus musculus) | 6480464 | CTD | 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form] | PMID:27638049 | |
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