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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620574
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cybb
Name: cytochrome b-245 beta chain
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cybbdecreases expressionISOCYBB (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of CYBB mRNAPMID:20458559
Cybbdecreases expressionISOCybb (Mus musculus)6480464CTDArsenic Trioxide results in decreased expression of CYBB mRNAPMID:28454374
Cybbmultiple interactionsISOCYBB (Homo sapiens)6480464CTD[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CYBB mRNAPMID:15894607
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