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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3426
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psmb8
Name: proteasome 20S subunit beta 8
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmb8decreases expressionISOPSMB8 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of PSMB8 mRNA; Arsenic Trioxide results in decreased expression of PSMB8 proteinPMID:15725085 PMID:19364129 PMID:27829220
Psmb8multiple interactionsISOPSMB8 (Homo sapiens)6480464CTD[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PSMB8 mRNAPMID:15894607
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