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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2796
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hk1
Name: hexokinase 1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hk1increases expressionISOHK1 (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of HK1 mRNAPMID:15761015
Hk1multiple interactionsISOHK1 (Homo sapiens)6480464CTDArsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HK1 protein]PMID:26598702
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