GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gabra1 | affects binding | EXP | | 728715 | RGD | Diazepam binds to Gabra1 protein | | Gabra1 | decreases expression | EXP | | 6480464 | CTD | Diazepam results in decreased expression of GABRA1 mRNA | PMID:11804615 PMID:15802192 | Gabra1 | increases activity | EXP | | 6480464 | CTD | Diazepam results in increased activity of GABRA1 protein | PMID:15613639 | Gabra1 | multiple interactions | EXP | | 6480464 | CTD | Diazepam promotes the reaction [Ethanol deficiency results in decreased expression of GABRA1 mRNA] | PMID:14684873 | Gabra1 | affects activity | ISO | GABRA1 (Homo sapiens) | 6480464 | CTD | Diazepam affects the activity of GABRA1 protein | PMID:15864560 | Gabra1 | multiple interactions | ISO | Gabra1 (Mus musculus) | 6480464 | CTD | Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]] | PMID:1712603 | Gabra1 | multiple interactions | ISO | GABRA1 (Homo sapiens) | 6480464 | CTD | Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Diazepam results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; Diazepam results in increased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Diazepam results in increased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form] | PMID:26344803 PMID:29038840 | |
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