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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732095 Species: Mus musculus RGD Object: Gene Symbol: Pcna Name: proliferating cell nuclear antigen

Acc ID: CHEBI:4917 Term: eugenol Definition: A guaiacol with an allyl chain substituted para to the hydroxy group. CasRN: 97-53-0 Chemical ID: MESH:D005054

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein]	PMID:20043298
multiple interactions	ISO	RGD:3269	6480464	CTD	Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA mRNA] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]	PMID:19851710