GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdk2 | affects response to substance | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | CDK2 protein affects the susceptibility to Etoposide | PMID:16217747 | Cdk2 | increases expression | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | Etoposide results in increased expression of CDK2 protein | PMID:16417649 | Cdk2 | multiple interactions | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein] | PMID:16417649 PMID:20149834 | |
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