GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bbc3 | affects response to substance | ISO | Bbc3 (Mus musculus) | 6480464 | CTD | BBC3 protein affects the susceptibility to Etoposide | PMID:20477944 | Bbc3 | increases expression | ISO | BBC3 (Homo sapiens) | 6480464 | CTD | Etoposide results in increased expression of BBC3 mRNA; Etoposide results in increased expression of BBC3 protein | PMID:21801448 PMID:25699604 PMID:37956312 | Bbc3 | multiple interactions | ISO | BBC3 (Homo sapiens) | 6480464 | CTD | entinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]; Etoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]; TP53 protein modified form inhibits the reaction [Etoposide results in increased expression of BBC3 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein] | PMID:25699604 PMID:37956312 | |
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