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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620625
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dusp4
Name: dual specificity phosphatase 4
Acc ID: CHEBI:4911
Term: etoposide
Definition: A furonaphthodioxole that has formula C29H32O13.
Chemical ID: MESH:D005047
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dusp4affects response to substanceISODUSP4 (Homo sapiens)6480464CTDDUSP4 protein affects the susceptibility to EtoposidePMID:16217747
Dusp4increases expressionISODUSP4 (Homo sapiens)6480464CTDEtoposide results in increased expression of DUSP4 mRNAPMID:29397400
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