• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736042 Species: Homo sapiens RGD Object: Gene Symbol: IGFBP3 Name: insulin-like growth factor binding protein 3

Acc ID: CHEBI:4903 Term: 17alpha-ethynylestradiol Definition: A 17-hydroxy steroid that has formula C20H24O2. CasRN: 57-63-6 Chemical ID: MESH:D004997

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 protein	PMID:10843175
affects expression	EXP		6480464	CTD	Ethinyl Estradiol affects the expression of IGFBP3 mRNA	PMID:20170705
decreases expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:16140622 PMID:17557909 PMID:17351261 PMID:15834898 PMID:12655037 PMID:16174780
affects expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol affects the expression of IGFBP3 mRNA	PMID:20170705
decreases expression	EXP		6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:18936297
decreases expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:16140622 PMID:17557909 PMID:12655037 PMID:15834898 PMID:16174780 PMID:17351261
decreases expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:15834898 PMID:17351261 PMID:12655037 PMID:17557909 PMID:16174780 PMID:16140622
decreases expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:17557909 PMID:15834898 PMID:16174780 PMID:17351261 PMID:12655037 PMID:16140622
decreases expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:17351261 PMID:16174780 PMID:12655037 PMID:17557909 PMID:16140622 PMID:15834898
decreases expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:15834898 PMID:16140622 PMID:17351261 PMID:16174780 PMID:12655037 PMID:17557909
decreases expression	ISO	RGD:2874	6480464	CTD	Ethinyl Estradiol results in decreased expression of IGFBP3 mRNA	PMID:12655037 PMID:15834898 PMID:16140622 PMID:16174780 PMID:17351261 PMID:17557909