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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733927 Species: Mus musculus RGD Object: Gene Symbol: Vldlr Name: very low density lipoprotein receptor

Acc ID: CHEBI:4903 Term: 17alpha-ethynylestradiol Definition: A 17-hydroxy steroid that has formula C20H24O2. CasRN: 57-63-6 Chemical ID: MESH:D004997

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Ethinyl Estradiol results in decreased expression of VLDLR mRNA	PMID:17555576
increases expression	ISO	RGD:3963	6480464	CTD	Ethinyl Estradiol results in increased expression of VLDLR mRNA	PMID:12075121 PMID:15901920
increases expression	ISO	RGD:3963	6480464	CTD	Ethinyl Estradiol results in increased expression of VLDLR mRNA	PMID:15901920 PMID:12075121