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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pparg
Name: peroxisome proliferator-activated receptor gamma
Acc ID: CHEBI:490095
Term: esculetin
Definition: A hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.
Chemical ID: MESH:C007628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargmultiple interactionsEXP 6480464CTDesculetin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of PPARG protein]PMID:21450970
Ppargmultiple interactionsISOPparg (Mus musculus)6480464CTDesculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA]PMID:27769711
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