• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61971 Species: Rattus norvegicus RGD Object: Gene Symbol: Kcnj5 Name: potassium inwardly-rectifying channel, subfamily J, member 5

Acc ID: CHEBI:4887 Term: ethosuximide Definition: Pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures. CasRN: 77-67-8 Chemical ID: MESH:D005013

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Ethosuximide inhibits the reaction [[KCNJ5 protein binds to KCNJ3 protein] which results in increased transport of Potassium]	PMID:18977371