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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70498
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfkb1
Name: nuclear factor kappa B subunit 1
Acc ID: CHEBI:48765
Term: dimethylarsinic acid
Definition: The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups.
Chemical ID: MESH:D002101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkb1increases expressionEXP 6480464CTDCacodylic Acid results in increased expression of NFKB1 mRNAPMID:26617437
Nfkb1multiple interactionsEXP 6480464CTDCacodylic Acid results in increased expression of and affects the localization of NFKB1 proteinPMID:26617437
Nfkb1multiple interactionsISONFKB1 (Homo sapiens)6480464CTD[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of NFKB1 mRNAPMID:23192986
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