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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2909 Species: Rattus norvegicus RGD Object: Gene Symbol: Kpnb1 Name: karyopherin (importin) beta 1

Acc ID: CHEBI:48765 Term: dimethylarsinic acid Definition: The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups. CasRN: 75-60-5 Chemical ID: MESH:D002101

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:10804	6480464	CTD	Cacodylic Acid results in increased expression of KPNB1 mRNA	PMID:17441966
multiple interactions	ISO	RGD:10804	6480464	CTD	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of KPNB1 mRNA]	PMID:17441966