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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735737 Species: Mus musculus RGD Object: Gene Symbol: Lef1 Name: lymphoid enhancer binding factor 1

Acc ID: CHEBI:48607 Term: lithium chloride Definition: A metal chloride salt with a Li(+) counterion. CasRN: 7447-41-8 Chemical ID: MESH:D018021

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter] Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter] Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter] Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter]	PMID:19582394