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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619869
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcl1
Name: C-X-C motif chemokine ligand 1
Acc ID: CHEBI:4806
Term: (-)-epigallocatechin 3-gallate
Definition: A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
Chemical ID: MESH:C045651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl1multiple interactionsEXP 6480464CTDepigallocatechin gallate inhibits the reaction [CXCL1 protein results in increased abundance of Calcium]; epigallocatechin gallate inhibits the reaction [IL1B protein results in increased expression of CXCL1 protein]; epigallocatechin gallate inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein]PMID:15237969
Cxcl1multiple interactionsISOCXCL1 (Homo sapiens)6480464CTD[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CXCL1 mRNAPMID:22079256
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