GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | affects expression | EXP | | 6480464 | CTD | epigallocatechin gallate affects the expression of TP53 protein | PMID:22000973 | Tp53 | multiple interactions | EXP | | 6480464 | CTD | [epigallocatechin gallate co-treated with coenzyme Q10] inhibits the reaction [Cisplatin results in increased phosphorylation of TP53 protein] | PMID:33393703 | Tp53 | affects response to substance | ISO | TP53 (Homo sapiens) | 6480464 | CTD | TP53 mRNA affects the susceptibility to epigallocatechin gallate | PMID:19406223 | Tp53 | increases expression | ISO | TP53 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in increased expression of TP53 protein; epigallocatechin gallate results in increased expression of TP53 protein modified form | PMID:26341291 PMID:32512070 | Tp53 | increases response to substance | ISO | TP53 (Homo sapiens) | 6480464 | CTD | TP53 protein results in increased susceptibility to epigallocatechin gallate | PMID:15764647 PMID:23285096 | Tp53 | multiple interactions | ISO | Trp53 (Mus musculus) | 6480464 | CTD | [epigallocatechin gallate co-treated with Polylactic Acid-Polyglycolic Acid Copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA]; epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA]; epigallocatechin gallate promotes the reaction [Benzo(a)pyrene results in increased expression of TRP53 mRNA]; epigallocatechin gallate results in increased expression of and results in increased phosphorylation of TRP53 protein | PMID:18656336 PMID:23717041 PMID:34600025 | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate affects the reaction [Doxorubicin affects the expression of TP53 protein]; epigallocatechin gallate inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]; epigallocatechin gallate results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein; epigallocatechin gallate results in increased expression of and results in increased phosphorylation of TP53 protein | PMID:15657356 PMID:15764647 PMID:15795422 PMID:19406223 PMID:35218280 | | ||||||||||||||||||||||
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