GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | decreases expression | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in decreased expression of AKT1 protein | PMID:35218280 | Akt1 | decreases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in decreased phosphorylation of AKT1 protein | PMID:23954321 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]]; [epigallocatechin gallate co-treated with Quercetin] promotes the reaction [Docetaxel results in decreased phosphorylation of AKT1 protein]; [epigallocatechin gallate co-treated with Quercetin] results in decreased phosphorylation of AKT1 protein; [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]; BMAL1 protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]]; Docetaxel promotes the reaction [[epigallocatechin gallate co-treated with Quercetin] results in decreased phosphorylation of AKT1 protein]; epigallocatechin gallate inhibits the reaction [HGF protein results in increased phosphorylation of AKT1 protein] | PMID:19244381 PMID:25655047 PMID:29061316 | Akt1 | multiple interactions | ISO | Akt1 (Mus musculus) | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [Imiquimod results in increased phosphorylation of AKT1 protein]; epigallocatechin gallate results in decreased expression of and results in decreased phosphorylation of AKT1 protein | PMID:29402411 PMID:34600025 | |
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