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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:479072
Term: 2-aminopurine
Definition: The parent compound of the 2-aminopurines, comprising a purine core carrying an amino substituent at the 2-position.
Chemical ID: MESH:D015075
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1multiple interactionsISOCyp1a1 (Mus musculus)6480464CTD2-Aminopurine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-Aminopurine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]PMID:1312672
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